Journal: Frontiers in Veterinary Science
Article Title: Improving the breeding capabilities of short-term estrus synchronized Ossimi sheep using pregnant mare serum gonadotropin loaded chitosan-nanoparticles
doi: 10.3389/fvets.2025.1607674
Figure Lengend Snippet: Diagram illustrating estrus synchronization procedures. Short-term progesterone estrus synchronization protocols using PMSG and PMSG-loaded chitosan nanoparticles were implemented. In Group 1, ewes were synchronized with 1 mL of Lutone (25 mg of progesterone acetate in oil) daily for 7 consecutive days. On the 6th day, they received 600 IU of PMSG (Folligon®), followed by 1 mL of Estrumate (250 μg of PGF 2α ) on the 7th day. Estrus detection was conducted with an intramuscular injection of 1 mL of Receptal (4 μg of GnRH) at breeding. In Group 2, the treatment regimen was the same as Group 1, except that on the 6th day, ewes received 300 IU of PMSG-loaded chitosan nanoparticles. Group 3 followed a treatment protocol similar to Groups 1 and 2, except for administering 150 IU of PMSG-loaded chitosan nanoparticles on the 6th day.
Article Snippet: On the 6th day, they received an intramuscular injection of 600 IU of PMSG [3 mL Folligon® (MSD, Intervet International B.V., Boxmeer, The Netherlands)], followed by 250 μg of PGF 2α [1 mL Estrumate (PGF2alpha analog, cloprostenol sodium, Coopers Animal Health Ltd., Berkhamsted, England)] on the 7th day.
Techniques: Injection